Go with a CZ 75 or derivative. There are people who shoot Bullseye pistol with them stock. Very accurate out of the box. Put a reflex red dot on it. Go shoot. A lot.
These guys can help with grips made to fit YOUR hand.Thanks for the suggestions everyone. I will add that I've got big hands. A model 19 doesn't really fit me: I can't get my finger in the trigger guard without breaking my grip from the gun and I end up pulling the trigger with the second joint of my finger (closest to palm). There is no way for me to contort my fingers in such a way as to use the pad of my finger, or even the first joint like a lot of folks do. So that's a major consideration and part of why I was thinking of going with a large, full-frame pistol. A generously sized trigger guard, changeable grips, and an adjustable trigger shoe would be very nice options to have!
Oh neat! I've been thinking I need to look for a different grip for the revolver to extend the pull some.These guys can help with grips made to fit YOUR hand.
http://www.herrettstocks.com/album.htm
Spendy, but you only have to buy them once.