I had excellent results with 223 Rem handloads using the 52gn Hornady A-Max in an 8-twist Lilja many years back - MV unknown. I was using up the remains of a stock of lighter bullets from a previous 12-twist 223. 'Excellent' was consistent quarter to third of an inch 5-shot groups at 100. This seemed a useful load for a sheltered 100-300 yard range I frequent.
This performance was obtained in working up over the winter in 30s-50s temperatures. On a hot summer's day (by UK standards) on the 300 yard range, the first half dozen shots were in the target centre as expected, then things went increasingly wrong with serious elevation stringing. ('Serious' as in 4 or 5 MOA!)
Switching to the rifle's usual 80gn load, I kept the 52s back until we'd moved to 100. Again, from a cold barrel the first group was fine before it went bad again in group 2 ..... then in group 3, I was either in a world BR record group situation as there was only a single clean-edged hole on the target, or shots two and after hadn't arrived. Yes, they were exploding in grey puffs 80 or 90 yards downrange. I couldn't see it, but spectators behind me said it was quite spectacular and quickly attracted a small crowd of rubberneckers.
These Hornady bullets are known to be very thin-jacketed and therefore vulnerable to over-rotation, but it shows the stresses any lightweight bullets are subject to in this situation.