For me a good supply of different burn rates, that perform in many different calibers, of different cartage sizes, and barrel lengths is something that took years to figure out. the same caliber with the same length barrel can require far different powder depending on cartridge size. But I also want efficient overall results.
A good example would be a 22 hornet, a 222, and a 22-250AI. H110, to H4350 in rifles all toting 24" barrels. all 22 caliber, and all using the same length barrel. I also can do the same comparison with 30 cal. using a 308 win, a 30-06, and a 300 win mag. Varget, H4350, to H4831, over the decades both these examples have proven to give me great results in rifles I have loaded with them.
then I said I looked and worked for decades finding a way to be efficient. I also shoot 600 yards or less for everything except Varmints, target shooting 600 max, most hunting 200 to 500 yards is what I limit shots at in the field. At those yardages, even 100 fps is meaningless, and more efficient is priority.
I also have seen consistent results also require using a powder that not only gives me upper end pressures, but also near 100 percent case fill. I use this concept for both handgun cartridges as well as rifle. Over the decades I have found powders that work well in all calibers, of different burn rates that cover most 22 to 24 even 26 inch barrels, and it makes for being able to buy kegs, being cheaper than buying by the pound.
The small list of powders, allows great accuracy loading various calibers that use cartridges that allow full case fill and near or at max pressure. this has eliminated my use of any ball powder in rifle cartridges. Decades ago I decided that most stick powders were far less picky in what they work well in, at least for me. Maybe this concept works for me because I have stuck with fewer powders to work with and am just more familiar with their use in different applications. My big bore handguns are the only thing I use ball, or flattened ball powders in.
The powders I have found to do 95% of my loading and give top results in various cartridges and callibers are H100, and HS-6 in handguns, H322 in smaller calibers, in rifle N130, N133 and N135 cover most short and midrange target cartridges, as well as most smaller varmint rifles. in my hunting rifles for big game, or extreme range varmints, Varget, H4350, and H4831 serve me for anything from 22-250 AI to 338-06. Add IMR 7828 and even the reasonable big Magnums are covered well.
Over the decades I have found very few instances that these powders can leave me wanting or needing anything else. There are many other powders that will give near the same results in some of the cartridges, but hardly much better, and none I've found to do as well in as many different cartridges as these will.
But trust me, I have loaded and owned most commercial cartridges, and nearly as many wildcats using these powders, and have found it not worth stocking others. If these powders wont give me great results with any cartridge I have loaded for, They are probably those that are on my list of the most inefficient cartridges ever drempt up, and on my list of cartridges that are not worth baggage to own! But hey I felt the same way about dating a prom queen,,,,,
I spent many years after being forced into retirement 40 years ago after a 42' fall and surviving, mainly reloading and experimenting with anything I had no experience with. This wasn't in my spare time or after work, this was my life, all I did, unless I was fishing, and pursued it the same way, making my own lures and flies most my own configurations.
But when I ran out of commercial cartridges, wildcatting got in my blood, and that what is opened my eyes to the benefits of wildcats. Not chasing speed, that became a needless biproduct. But finding a way to blend that need for speed with the most efficient way to do it with accuracy the priority. Decades ago that is why those big belted Magnums, and cartridges that required overbore cartridges.
Why would I load a 257 Weatherby, that requires over 40% more powder, to give me less than 10% in performance, and never the accuracy the smaller 257 Roberts AI would? Even the overbore 25-06 would be better choice, but not come close to the Bob AI for efficient and never more accurate, for maybe 50 fps, 25 to 30% more powder to get 5 to7% more speed, and never give better accuracy. I just quit chasing these meaningless results, when I discovered what efficiency was really all about.
Keep it simple, it makes life more fun, and less expensive, while you stay as capable. Don't let folks make you chase meaningless wants, as they are only measurable with a chronograph, and in most cases at the obvious expense, easily recognized on the targets! Find powders that work in a wide variety of cartridges and calibers. Even chasing the most accurate loads, few top the powders I listed.