I have managed to blow up varmint bullets in 7 twist. I was only testing some firing pin spring changes and my only concern was ignition, but many of the 40 and 50 VMax rounds turned into a grey puff just beyond the muzzle, and those were only 223 velocity. YMMVI have some 50grn varmint grenades and a 7 twist 22-250AI I wanted to try and was wondering if I was wasting my time……