Footage from Expert-Tube shows 22-Creedmoor has very short Barrel Life.
........... as will 22-250 and 224-6.5X47L. Canadian F-Class shooters adopted the 22-250 shooting 80gn Sierra MKs in 1:8 twist barrels in the very dawn (pre F-TR introduction) of the discipline. Barrel accuracy life was around 900 rounds it was said, 1,100 at most. Running the 10% higher capacity and much stronger X47L case at higher pressures and with 90s vice 80s, it'll be considerably worse. I read somewhere that hardly any of the Canadian F shooters rebarrelled with another 22-250 when the first was shot out thanks to this factor - MVs and precision were fine, but just too expensive in a high round count discipline. (Bear in mind too that like us in the UK, Canadian sling and F shooters pair-shoot which is much kinder to barrels than US string shooting.)
A lot therefore depends on the discipline and its annual round counts. A hot 224 makes more sense in BR than in F-Class (where the competition in F/O is the 284 and other 6.5s and sevens that will always offer better external ballistics than any 224 in any event as well as better barrel life). A friend uses a .22 Dasher 'Light Gun' for 600 BR shooting 80gn VLDs and puts up some excellent groups and aggs and has had a lot of class wins and match smallest groups with it at this distance. That's probably as large a case as I'd consider for the calibre, and the various BRs also have small primer / flash-hole cases (as does the 6.5X47L and some makes of Creedmoor) which I'd also want. There's a lot to be said for the plain .22BR version though.