I think James is now on the right path. I assume you got him headed down the right path.
As I said, I've not been able to distinguish one sweet spot as being better than another. Of course, I don't change the load after settling on a good one and I simply maintain tune with the tuner, using my method.
I tune the load without touching the tuner. Once I establish a good load, I then move the tuner a mark at a time, and watch the groups open and close back up. Typically, there are about 4 marks between in and out of tune within a given node, with my tuner. Once you establish this area in relation to marks moved, I continue to shoot to establish how far it takes to bring it back into tune. Again, this is typically about 4 more marks. So, what I've established now, is how far between in tune, to completely out of tune, and back in again. This is a total range of about .008" of tuner travel and represents total node width in relation to the marks on the tuner. Once done, you can go back to your "in tune" setting and the groups will get bigger if moved either direction from here. Same is true for a completely out of tune condition...If it's completely out, moving either direction will improve it..but in this example, which is very typical of br barrel contours and chamberings, you'll never be more than 4 marks from in tune. In use, 2 marks is a pretty big adjustment to maintain tune. The reason for shooting at each mark for at least 8 marks is to see and familiarize myself when how groups will form and what they look like at any point within the node. This is very useful info for making adjustments when needed. Once familiar with what groups look like at various states of tune, it's very easy to know how far the tuner should be moved to bring it back in.
This all sounds like a buch of constant twisting, but it's not at all. In reality, I seldom need to move it much if at all and that's almost always done during the warm-up and checked between yardages. Another thing is that node width in regard to tuner movement is not indicative of how well it stays in tune during a match. I prefer a tuner design that allows for me to take the rifle completely in or out of tune in a small range of motion because it greatly simplifies the whole process, but again, it has nothing to do with how wide the tune is relative to temps or other conditions.
This is my experience and what works best for me. I look at a tuner that is never touched as simply being a barrel contour that incorporates a dog knot at the muzzle. I work up a load for it just like any other barrel, stay with that load, and only nudge the tuner when needed..similar to changing the load to maintain tune but with less stuff to pack to the range.

--Mike