Cartridge efficiency is what can make one cartridge more accurate then another.
When a smaller capacity cartridge, can produce near equal velocities for a given bullet weight, it is more efficient, hence; more inherent accuracy.
Cartridge Efficiency:
(Bullet Weight * .5) * (MV ^ 2) / (Charge * Joules per grain) / 98000 = % of efficiency
Note:: (kJ/kg / 15.4324 = Joules per grain)
Examples:
6Dasher:: 105-VLD <> 3000-fps <> 32.5 of RL-15 = 57.4%
243-Win:: 105-VLD <> 3000-fps <> 44.5 of H4350 = 44.9%
44.5 H4350 in a 243 Win with a 105 VLD would be pretty hot by my experiences with that combination,,