There are two slightly different approaches, dependent on whether the reloader cares about jamming bullets or not:
VLD bullets are designed with a secant ogive. This ogive shape allows bullets to be more efficient in flight (retain more velocity = less drop and wind deflection). While this result is desirable for many rifle shooters the secant ogive on the VLD bullets produces another result in many rifle.
bergerbullets.com
The issue I assume you are referring to is the potential change in operating pressure across such a wide seating depth range. The simplest answer is that a charge weight that is safe at either 0.120" or 0.130" off the lands (i.e. the seating depth
farthest from the lands in the test) should also be safe for the remainder of the seating depths. If that specific charge weight is not providing sufficient velocity for rounds seated closer to the lands, you may have to tweak it a bit.
Trying to cover that wide a seating depth range with a
single charge weight may not always be realistic with all cartridges/powders/bullets, etc. Nonetheless, it is a way to cover a very wide seating depth range in order to find a much smaller seating depth
region where a given bullet appears to shoot better than at any of the other seating depth region in the test. In other words, it is a very coarse test, but it covers a wide range. By nature, such tests are used initially to point one in a certain direction, with the expectation that you'd then go back and cover the specific region identified in the initial test using a much finer seating depth increment. At that point, you'd be covering a much smaller seating depth window and so pressure due to changing the effective case volume wouldn't be such an issue.