Not sure anyone has had them in hand long enough to do significant testing as yet. I'm also curious to see how they compare to the 200.20X. The box G7 BC of the 208 is 0.354, whereas in my hands, pointed 200.20Xs generate G7 BCs on ~0.340 to 0.350 range, based on LabRadar velocity data. Note that the 208s come already pointed from the manufacturer, which means you're not likely to be able to improve the BC value much, if any, at home. Effectively, those BC values are the same, only differing in the third decimal place, meaning you can point the 200.20Xs at home and effectively achieve approximately the same BC as the 208 straight out of the box.
The external ballistics of the two bullets will ultimately depend on the velocity at which the 208s will tune in. With a 30" barrel as is commonly found in F-TR, I'd expect them to tune in somewhere in the 2600 fps range with Varget, or about 50 fps slower than the 200.20Xs. With the two bullets having effectively about the same BC, I'd guess that the 200.20X might even have a slight advantage in wind deflection, at least in theory. The 215s hybrids in a comparable rifle tune in with Varget at ~2550 fps, or about 100 fps slower than the 200.20X. In theory, the 215s at 2550 fps enjoy a small advantage over the 200.20X going 2650 fps at 600 yd, slightly more at 1000 yd.
How the new 208 and 220 Hybrids compare to the existing designs will depend on exactly what velocities they tune in, and how good their consistencies are. Even if the wind resistances are only about the same at their velocities in tuned loads as the 200.20Xs or 215s, if the new bullet designs have more consistent QC, i.e. their BCs are more uniform bullet-to-bullet, I think you'll start to see a lot of F-Class shooters using them.