Anywhere a chambered banana can bind.
Upper body, shoulder, neck, bullet.
If your loaded ammo measures 2thou of TIR at body-shoulder junction for example, and if this puts a case in interference with your chamber, then that is a pressure point that is likely less than consistent.
A high number of FL sizing cycles could put you there.
If you make dead straight cases, but your seating causes 3thou TIR at exposed bullet bearing, then you'll likely force interference with freebore. The case may not be able to lie angled enough in a tighter clearance situation to relieve pressure at that freebore.
But your reloading has to be really bad to cause all this.
And maybe you'd embrace the 'rat turd in a violin case' relief, as it must seem easier than good reloading.
It's just way different from my view of things.