I run N160 exclusively in my 6SLRs. H4350 is an exceptional powder as everyone knows, but it is very hard on throats compared to N160. I have 1,468 rounds on a prone gun, 30" barrel, .236 bore, that I run at 3,250fps with moly. I've never had any pressure issues with it. It would shoot 5"-6" of elevation at 1k. Borescoping it shows minimal checking at the lead with almost none forward of that. It looks comparable to a 6.5x284 with 300-400 rounds. I have a good friend whose 6SLR went south at around 2,700 rounds. His throat was much shorter than mine and he was running just under 3,100fps, but was very accurate. He won the LR Regional at ORSA last year with it. I have another one up and running for PRS type matches. 26", .237 bore, 7.5 twist that is currently running 44.7gr N160 at 3,115fps with moly in cold weather testing (40*). It has only 60 rounds or so. It is an great cartridge in every aspect. Very easy to form, easy to load, great accuracy potential, low recoil, great barrel life with the right powders. I don't chase barrel life, but as a byproduct, I will take it.