Dave T: It may boil down to your prime interest in what you want to do with the Cooper. I've had 3, 22-250 chamberings, excellent cartridge for what it was designed for: Varmint hunting, with very good accuracy as a bonus. Over the last 5 to 6 years I've been able to compare a very accurate factory Remington 700 ( 26" fluted, stainless, 1-14 varmint contour) with several of my 6BR's, both 14 & 8 twists, and in every comparison where accuracy was the consideration, the 6BR came out the clear "winner". Just recently pulled the barrel from that Remington, and it also wears a Krieger 14 twist heavy contour 6BR barrel now. I know in this instance I'm comparing a factory barrel to custom hand-lapped ones, but I previousely had a Hart 14 twist in 22-250, & while an excellent shooter, it also did not meet the accuracy standards of the 6BR ctgs. All 3 22-250 barrels were toast at a documented count of between 2300 & 2400 rds. fired. My highest count 14 twist 6BR now has 1680 rds. fired with not a trace of firecracking in the throat, as seen with my borescope, so I'm expecting to exceed the 2300/2400 of the 22-250. As sleepygator said, the choice of match grade bullets, of extreme accuracy, in 6mm covers every choice you could want. In our local competition BR match's I see very few 22 calibers being used: the vast majority are 6mm's. So: varmint hunting, go with the time proven 22-250. If leaning toward more accuracy, go with the 6BR. And yes, I also have a 22BR, but seldom use it & it too is a prime candidate for another re-barrel to ?, probably another 6mm.
