All:
I thought I would chime in, I am no expert - just a lifelong tinkerer and experimenter. I compete in both RF and LR Highpower, and years ago it made sense to me that we could alter engraving depth in RF just like I did with seating depth (and other variables) in HP to optimize barrel / ammunition performance.
For what its worth, I am still using the same chamber profile with Lapua ammunition - a 1.5 degree leade angle, shallow taper chamber based on the old Meyers chamber - set up to engrave .030". I have used it to win four National Titles, and I am really happy with it. It has consistently outperformed all of the other profiles I have used in many different barrel configurations (and there have been a bunch over 25 years of shooting and smithing RF rifles).
Seating depth IMHO serves several functions in RF - the engraving must be sufficient to provide an optimal starting point and gas seal, and must provide sufficient clearance at the case mouth for the accumulation of debris over an adequate number of rounds to maintain accuracy (in my case, I use approx. 200 rounds as a benchmark - so I don't need to clean between prone stages).
Any chamber (RF or HP) requires attention to concentricity and great internal finish (especially in the leade area) to perform well. The 52D chamber is a fantastic chamber though - I used it for many seasons prior to becoming a sponsored shooter. I would not hesitate to use it again, as it performs very well with virtually any bullet profile. As I have mentioned before, the 2 degree leade angle typically used for the EPS profile is fine for Lapua ammunition also - and is probably more tolerant overall for those testing all manufacturers ammunition. When I started using the 1.5 degree chambers, it was simply to find something optimal for Lapua, that's all.
Regarding tuning - this is controversial (and just my very humble opinion), I think what we are doing with the manipulation of mass is timing the exit position (as the muzzle oscillates). I believe the most forgiving settings are those when the muzzle reaches the outer edge of the oscillation (and slows to reverse course). I can see this during testing - a great group bordered on either side by good / round groups. Speed would also effect exit point (faster rounds arriving earlier in the exit oscillation, slower later), and I believe that once a certain muzzle velocity is used for tuning, similar velocities would therefore be a great starting point for subsequent lots. Most would tell you that once a rifle is "tuned", it never needs touched again - but I have found that if a great lot is found of a different speed retuning is necessary to optimize it.
Wishing all of you the very best,
kev