The post was placed for folks with an open mind.
Harold Vaughns Ladder will work with any cartridge.
I have my own method too.
Usually I want the high node so I concentrate there and also for the cartridges that I've used for years I know approximately where to start the powder charge range. For the medium sized cases and smaller ones I use .1 grain increments for the large one with a 80 grain capacity I use .2 instead. I feel doing it this way gives me most, if not all, the info I need in one trip.
My recipe is picking a clam morning and the earlier the better, that often means, or what seems most advantageous anyway, is a day or two after a weather front has past through and before another comes in.
I like doing ladder testing for the more accurate rifles at 400Y or farther if possible now but I'm still learning my lessons. The reason why is a more accurate rifle can put most of the holes too close together at 300Y which can be confusing. In fact the last ladder I did at 250Y for a small varmint cartridge all 14 shots except for one were crammed into 1.25", I got the info I needed but I got lucky because 3 consecutive shots went into .3". This time I picked the low node because .3" at 250Y was fine by me for that cartridge and I wanted to extend barrel life as a side benefit. There were other reasons I used 250Y but I won't go into it right now.
It's a total pain but I drive down to mark each shot, my reasoning is the barrel cools the same amount for each shot which has been optimal for me due to past failures when I first tried ladder testing when I let the barrel get too hot.
The ladder I did before the one I just mentioned was also 14 shots in .1 gr increments, the last 3 consecutive were touching at 323Y so I didn't bother with a seating depth test. I pretty much have that down because my same reamer is used every time and that depth works well for the same bullet I've been using.
It doesn't always work perfectly. I've had to scratch my head and try again another day which was the time before these last two tests I just mentioned. On the first test for a big cartridge I discovered I was over a full grain lower than the high node, I got lazy and assumed when I stopped that the last charge would be plenty hot, nope I should have kept going, worse come to worse all that was needed was some bullet pulling when I got home but that mistake cost me another trip. For the second test I found the high node and it all came together, 3 consecutive shots into 1/2" at 400Y.
What I've observed is if it's mostly calm out when you do your ladder, is a node tightens in the horizontal like it does in the vertical, which makes picking a load easier.
I'm not a benchrest shooter so I don't have the accuracy requirements many do so there's that. I suppose further tuning could be a benefit but if I can get 3 shots into sub half moa I'm happy.