Slower burn rate is the exact reason I'm interested in trying 4064. With H4895 and 90 VLDs, somewhere around 2850 fps is a very nice sweet spot for a 30" barrel. The problem is that a number of people using that load (or similar) in F-TR in the last couple years have been having issues with jacket failure. One approach to help minimize this problem is to use a powder that will NOT give quite as much velocity as H4895 in an optimized load, thereby removing a little stress on the jacket. The key will be to find a powder that gives slightly less velocity in an optimized load, but not so much less that you're giving up too much performance. My estimate is that a powder that would give a velocity of somewhere around 2800 to 2820 fps from a 30" barrel ought to be just about perfect.
Varget is one choice that will typically give velocities that are about 20-25 fps less than H4895 in a tuned load. However, a kernel of Varget is almost half again the weight and size of a kernel of H4895, which may not be optimal for maintaining low ES/SD in the small .223 Rem case. I'm looking for additional choices, and 4064 falls within a reasonable burn rate range, and is also known to pretty reasonable resistance to temperature-dependent velocity variance. However, if the kernels are even larger/heavier than Varget (as I suspect they are), 4064 may not be the best choice. IMR4166 would probably also fit the bill in terms of its other properties, but the kernels are substantially larger than even those of Varget. Varget will certainly work, and I have plenty of it. I'm just checking whether there might be a few other options that are worth looking into.