I also agree that that is HOT. That equates to a 2900+ from a 24" barrel.That's hot as hell with 156s. You're around 74k psi.
I consider H1000 and N565 to be basically identical in terms of charge weight and case fill in the 6.5 PRC. I personally run around the 58.3 to 58.6 gr region with H1000 vs N565 and 143 ELDX to achieve 2950 out of a 24" barrel.
With those loads I would worry less about annealing and more about your primer pockets. Not sure your primer pockets are going to go the distance if you are looking for double digit firings.