As a re-loader, you will run into issues like these. Best thing is to write a list of all possibilities and begin a process of elimination. Here is what I'm thinking. You did end up with damp powder as evidenced by clumping powder. Lesson learned is to warm your brass in oven at lowest setting or a brass dryer until you are certain all traces of moisture are gone. Still - I don't believe there was enough moisture in them to cause the primer to not pop, given you blew them with compressed air. You didn't deepen the primer pockets - so unless your brass is faulty enough to cause misfires (very unlikely), the brass and primer pocket seating depth are not likely the issue. My $10.00 says you pushed your necks back too far with your die setting. If you have a Hornady headspace measuring tool that you put on your dial caliper (or other brand of tool), measure all of your fired cases and compare to the measurements of a fair number of ready-to-fire ammo you have not yet fired (if you have any). If the fired cases are more than .005" longer from base to shoulder than that of the unfired, it shows you that you bumped the shoulders back too much. It could have been .010" too much. I'd take your absolute longest fired case and use this as a temporary basis for setting your shoulders back on your next batch of ammo. I'd bump them no more than .002" is bolt gun and .004" if in semi-auto. Then, do the same comparison of your fired/unfired cases again. I'm betting your new .002" setback length will be considerably longer than the measurement you used to load your first batch- which indicates they were too far back before. The Remington 7 1/2 primers have a little thicker cups which means they need to make solid contact with a firing pin that won't merely push an "unsupported" case forward. If your case was too short, the firing pin merely pushed the case forward -or it was sitting "loosely" and too far away from the firing pin in the chamber - resulting in sporadic misfire when struck. If it turns out that your fired brass measurements reach a certain point that no individual case exceeds, though several reach the same longer measurement - that is most likely the measurement you want to use in the future to set your shoulders back. After all that - and still having problem with dry cases and powder, fully blown-forward shoulders, primers seem to be sitting just below being flush with the brass, I'd re-examine your bolt assembly to ensure no grit or carbon is preventing full firing pin extension, as well as the condition of the tip of the firing pin. THEN I'd look at the possibility of bad batch of primers. Good luck!