It's been my operating theory that everything we do the "fine tune" a load is all about barrel time and getting the bullet to leave the muzzle while the harmonic reflection is nearest to the chamber end of the barrel.
To that end, charges vary exit time in large steps, and bullet seating varies it in small steps, and the target tells you which way the muzzle is pointing when the bullet exits, presuming the shooter can execute the shot consistently. (HA!, I know that's the biggest hurtle for me)
So I start with the bullet seated either .010 in the lands or .020 out and work the charge, then adjust the seat, then neck tension, then primer, then consider purchasing a(nother) new barrel...LOL