Being the idiot that I am, I have to test. My use is field use and after I work the load the best that I can at the range I take it to the field and test more. At the range we get predictable winds because the wooded area has not changed in 5 decades, nor has the open areas so the variations in the wind are limited and my knowledge of how it reacts from the firing line to the target is extensive. In the field things are catch as catch can, I don't always have significant knowledge of how the lay of the land affects the projectile. This type of study helps me pick the final load better, terraced fields may have many eddy currents and hyper velocity can help.
Not having any idea (nor caring) why but my 223 and my 6MM Remington both produce very good 100-yard groups with light to medium weight bullets for the caliber. With that said I see it as an advantage as the vast increase in velocity, (500 to 600 FPS more) that I can get with a 40-grain vs a 60+ grain projectile is amazing. Similar can be said for my 6MM Remington with a 75-grain vs 100+ grain projectiles. What I have found is that the reduced time of flight helps reduce longer range group size as the wind speed increases.
On easy days the 223 is very effective out to 350 yards, on very calm days I have taken shots and made solid hits out past 400 yards. As the wind goes up, I move on to the 6MM Remington, which is very effective in moderate winds out past 400 yards, I've made hits out to 600+ yards. I'm not sitting there in a field and taking 3 or more shots at a chuck, my old man would crawl out of his grave and choke me.
The advantage I see for the field is not only better groups in wind but a reduced arc in the trajectory which helps with range estimations. The higher velocity is advantageous with wind eddy currents that run through the gullies in a terraced field. I'll take a 1/8" bigger low wind 300-yard group if the same load produces a 1 1/2" smaller group in higher wind.
The disadvantage is that I have good reason to suspect (via testing) that both of these rifles can produce better on range groups at long range with heavier projectiles if I can get some experience with the wind at the range and dope it well.