I am looking to purchase a reasonably light walking varmint and predator rifle. The two cartridges I am interested in are the 223 Rem and 22-250, Coyotes and cougar will also be on the list of things I will hunt with this rifle. It seems like almost every factory rifle in 22-250 comes with a one in fourteen twist and that 223 is either a one in twelve or one in nine twist. 223 factory guns are set up more to stabilize heaver bullets and the 22-250 looks to have the velocity and power advantage. I know shot placement is critical in any hunting situation. Which of these two cartridges would you choose knowing that a cougar could be a potential target? Which makes more sense as a all season kicking around in the hills kind of rifle? Whats barrel life like on the 223 and 22-250? Just narrowed it down and looking for a second opinion.