DoubleJake,
Son, if you shot that 50 5X, STICK WITH IT! That's a dang fine score and a nice target. Keep doing that, and maybe you'll be able to string some of those 50 5X targets together. Do that often enough, and you got this! If you shot that score with the old barrel, go back to the old barrel.
Tony Boyer wrote in his book that he could tell if a barrel would shoot or not in around 15 rounds. Now, Boyer was the greatest group shooter ever, so there's that, but if you've honestly got 400 rounds down the tube and all you're getting is garbage, well, a lot of folks wiser than me have weighed in on what to do.
I recently put a Pac-Nor barrel (thanks for the recommendation, Randy!) on my Panda, and within 50 rounds I found several 3-shot groups in the ones. That's testing two different bullets, one powder (differing amounts by .3 grains), and one primer. And I placed that amazing barrel on a proven chassis with proven components (action, scope, trigger, stock, rest/bags, etc.). Further testing revealed a load that, in perfect conditions, consistently shoots 3-shot groups under the ones. And, this is a 30BR.
All I need to do is learn how to steer it better in non-perfect conditions - LOL! The gun and that load flat-out shoot. Now it's on me. And my successfully reading conditions. Which is a lot...
Assuming you have a proven chassis, rest and bags, flags, brass prep, loading techniques, plus all the other equipment you need; and if all you changed is the barrel (excepting the world-class advice provided by many already), then you need to get a different barrel. I say Pac-Nor, but YMMV.
Oh, yes, the chrono. Don't forget about it, but understand that what you do on the target is far more important than EV and SD and other data. Maybe, through your chrony, your barrel is telling you something. LISTEN to it!
Again, if you shot that 50 5X target, then go back to whatever you did when you shot that score, and keep doing it. Keep your old barrel til it stops delivering great results. Then go Pac-Nor.
Just my .02