It is a well known fact that 4895 is great for reduced loads. Not so much with 4198! Personally I would not take the chance just because I have a certain powder.
Paul
Go back far enough and IMR-4198 was widely recommended in reduced velocity loads with jacketed bullets. My first reloading manual around 40 years ago was Speer #10 which showed a reduced load combination as the final table entry for most cartridge - bullet combinations and 4198 was the norm. They came with all sorts of caveats, but the primary one was warning against
under-loading (the concern being a bullet stuck in the bore, also jacketed bullet velocities become inconsistent at too low pressures / MVs because of their high friction in the bore compared to lead-alloy types).
The next edition, No.11 of 1987 still had reduced loads for many cartridges, but most had now changed to DuPont SR-4759, sensible as this propellant had originally been developed for this very purpose for the US Army for its bullet testing in 30-06. IIRC DuPont had withdrawn it, but then briefly reintroduced it for the handloading market in the 1980s.
A few 4198 loads remained in Speer #11. For instance, .30-06 with 180gn bullets. Start load: 26.0gn / 1,723 fps; Max charge: 30.0gn 2,000 fps. After #11, Speer dropped the reduced loads for whatever reason.
H4895 is an excellent reduced load powder, but for combinations that are closer to standard pressures and velocities. Take performance down far enough and you need a faster burning powder. Ideally, this should be a specialist grade such as SR-4759, today's equivalents being Hodgdon Trail Boss, Accurate-5744 and Shooters World 'Buffalo Rifle'.
This is all by the by. I'd not consider 4198 as an at all suitable grade for the 6.5 Creedmoor in any normal use.
With 4350 shortages, there are many suitable alternatives. (Whether they're actually obtainable in the USA I can't say, being on the others side of the Atlantic.)
For 4350 equivalents, consider Alliant Re16 and 17; IMR-4451 Enduron; Ramshot Big Game and Hunter; Lovex SO65 and SO70 (Shooters World 'Long Rifle' and 4350 respectively); Norma URP and 204, Vihtavuori N550, N160, and the new N555 developed for the Creedmoors; Hodgdon H414.
For the next faster burners which are still usable in many 6.5 Creedmoor loads: Alliant Re15 (and TS 15.5 when it appears); Norma 203-B, Viht N150, Lovex SO62 (SW 'Precision'); Accurate-2520.