Magnum performance and long barrel life? Aint that what we are all after(besides accuracy).
Anyway, I think you should seriously look into the 6.5 4S. GA Precision`s iteration of the 6.5 SAUM. This thing is a beast. 3150fps with 140s is a mild load, no big deal; and if you run it like that consistently Mr George Gardner is claiming 3000+ round barrel life. Maybe he just got a good barrel, but personally, I trust his word to say the least. IMO that man is not the type to lie and blow smoke. If you want a serious long-range Elk busting hammer, you can push 160gr Matrix VLDs at 3000-3100 fps or more according to Mr Rich(elkaholic on LRH) with his 6.5 Sherman Shortmag(6.5 SAUM). Thats a .680 G1 BC bullet(conservative estimate) at 3000 fps(conservative load)! Thats on the heels of a .300 Win Mag running 215gr Bergers at 3000 fps!! And the sectional density and penetration of a load like that combined with its size/recoil simply cant be beat. Youll basically have something with penetration akin to, well, as I said a .300WM with 215gr Bergers or 230gr Bergers. By all accounts, the 160gr Matrix bullets are serious business and perform admirably on large game. I really dont see why the 6.5 SAUM/160gr Matrix combo is not being embraced more heavily outside the LR hunting community. Most of the guys at LRH.com get it, but Im telling yall, that SAUM/160 Matrix combo is a force to be reckoned with and IMO will catch on like wildfire soon if brass availability goes up. For a SHORT action cartridge, its gonna be hard to beat. I emphasize that, because, atleast in Mr Rich`s case, with his 6.5 Sherman Shortmag version of the SAUM, he shortens the case slightly to around 6.5 Creedmoor length, so you get a true short action cartridge. IE; the 6.5 SS can be loaded on out there with 140s or 160s at mag length.
Speaking of elkaholic though, if youre considering a .280AI you also must consider the .280 Sherman. Its basically a .280 Gibbs with a longer neck. Has all the same case body dimensions as a Gibbs case but its formed from a .270 Win case or 6.5x65mm case so you end with a longer neck. Must say a glorious cartridge. This will do anything/everything the 7mm SAUM will do with widely available brass. Im really surprised noone thought of it sooner. I cant remember the exact numbers, but he basically took a .270 cartridge case, pushed the shoulder forward/shorter neck(IIRC .290" length neck but I could be wrong), blew out the case taper to like .012, 40-degree shoulder, and obviously necked up to .284. Im going off a real foggy memory here so correct me if Im wrong on any of those numbers(very rough estimates). But anyway, in talking to elkaholic, according to him the H2O capacity of the .280 Sherman came out to around 72-74gr H2O. So youre easily talking about SAUM, if not WSM territory in regards to velocity. 180gr Bergers at 3000 fps wouldnt be too much trouble. I wouldnt be surprised to see that case push them to 3100 fps. Its really a brilliant idea. Hes also got a 6.5 Sherman and .300 Sherman as well. And then the 6.5 Sherman Shortmag. Id really like to get a hold of a Pre-64 M70 or maybe a beat-to-hell M1917 Enfield or 1903 and chamber/rebarrel it in his .300 Sherman. Apparently hes getting 3100 fps with 190gr bullets of his own design. LOL 3100 fps with 190s in a `06 sized case, thats insane obviously .300 Win Mag territory. To be sure though, I dont know the specs on his 190gr "SXR"(as he named it) bullet design but Ive seen them and they look to be VLD profiles with aluminum tips. It could have a very short bearing surface, but either way 3100 fps with 190s in what amounts to a .30-270 Win-Improved is downright impressive.
If I was building a F-Class Open rifle, I would seriously consider the 6.5 SAUM and .280 Sherman. With the Sherman, you will not find a faster cartridge from a `06 size case/.473 bolt face, its basically a .280 with 7mm SAUM performance. With the 6.5SAUM, well, you basically get .260 barrel life with performance akin to brass-busting 6.5-284 loads if the 3000+ round barrel life is truly the norm with mild loads.