For load development at 100yds I use the target below. I expect the group POI to move as elements of the load are varied. So concern about obliterating the aim point is minimal, and needs to be controlled by how you zero the rifle in any case.
Minimal use of the color orange gave best visibility for me, all things considered. The center dot combined with the crosshairs controls POA pretty well for me.
I drew the target myself using the free download Open Office (Draw). The color, size of the center dot, crosshair lines, etc were varied to work with my scope and magnification at 100 yds.
Whatever element I am varying is written under each target and there's room for all the other relevant data in the middle. After use, the target is scanned, measured and saved to disk by OnTarget, and both copies are stored. The data on the target is also stored as a line in that rifle's Excel workbook along with MVs, a link to the target pictures, and other notes.
If anyone is interested in using it, or using it as a starting point, I can make the .ODG file available.