Ok...I’ve decided on my next rifle.  I really appreciate all the input!
Winner is:  25x45AI
Runner-Up:  25PPC (will build a bolt body and barrel at some point)
(Ended up in a totally different place than where I started)
Reasons:  Simple, Efficient, Precise, different, and “AllThingsAI”! 

.  Everything is easy to come by or modify.  I’ll have a 223AI, 6x45AI, and a 25x45AI.
Questions:
1.  Neck diameter for no-turn?  I’m thinking ~0.282”
2.  Need a .25 cal throater (any out there?)
3.  Action...Big Tikka fan (anyone have a T3x .223 action for sale?)
4.  Chassis?
5. Barrel twist...thinking 1:10 but I need to do some math.  I want to calculate the centripetal force vs RPM for a .257 bullet.  My Hypothesis is more CP force = more instant fragmentation...but there is probably an accuracy trade.  (I may do a more scientific study on this for fun).
I’ll start a new build thread and blog as I go.  Any interest in a thread like that?
I really appreciate all the input!  Such a great forum.
Ryan