MarkT, I did not look to see where you are hunting, but if in the south, deer are smaller, with less hair this time of year. it matters with a varmint bullet. Northern deer with more hair and fat do not make a good combo with varmint bullets. All the culls I have sot were late summer deer, little hair, little fat.
I stand by my thinking...if you must use a 22-250 with a varmint bullet, wait for a relaxed squared standing still broadside and slip it into the ribs right behind the point of the leg/shoulder. I like lower rather than higher...about 4-6 inches up from the breast bone. A vmax will hit those close side ribs, tear one heck of a hole, drive the ribs and bullet fragments through and most of the time you will skin it and find holes on the other side too, as it busts ribs there too...with chunks of ribs from the close side, lungs, heart and soup on the outside of the far side ribs. Makes a mess of the ribs, but personally, I dont eat them, so other than a diaphram forward blood soup at field dress time, no issue. The point is, there is no margin for error. A hit back of the diaphram and you have one heck of a nightmare, and one very hurt deer suffering needlessly.
If you can, try the TTSX with the 22-250, if that is all you have. It will drive through, and you can break a shoulder with it.
All that said, maybe you should go up a bit in caliber...maybe a 7 mm,,,,even a mild 7mm like a Waters from a TC or a 7-08 and a 120-140 grain bullet and you are all over it...
Or if you must, a 6mm...using a decent 85 to 100 grain bullet. I am thinking TTSX again, or a partition, just so that raking shot makes the grade, cause not all deer stand quietly sideways while you pop them. (In my world, NONE of the big ones do...they just show me the tailgunner eye under the white flag as it goes Bye bye!)
And go get another one! tell us how it goes!
