I have tested IMR4895 in both .223 and .308 loads with heavy bullets (90 gr and 185 gr, respectively). Both are cases in which I regularly use H4895. If you load to OBT nodes, IMR4895 will generally net you about 20-30 fps greater velocity than H4895 on an OBT node. In my hands, the pressure differential at the OBT nodes is negligible, in fact, IMR4895 is predicted by QL to give lower pressure in one of my loads, even though the velocity is slightly higher.
With regard to Laurie's comment about case volume and IMR4895, I had an issue with a compressed load at the OBT node in virgin Lapua .223 brass. The cases were definitely filled up and seating bullets was challenging in the OBT load in virgin brass. The average weight of a kernel of IMR4895 is about half again the weight of a kernel of H4895, and slightly higher than a kernel of Varget. I find the IMR4895 kernels are also more irregularly shaped than H4895 or Varget. Together, those two parameters suggest to me that IMR4895 may not pack into the case quite as well as H4895, which has slightly smaller and more regularly-shaped kernels. In the case of the .223 load, once the brass had been fire formed and resized, the increase in case volume was enough to take care of the compression issue. It was only an issue in virgin brass.
The main reason I have not routinely used IMR4895 in loads for competition as yet is a concern about the temperature-sensitivity. According to the temperature data I have found, IMR4895 is more sensitive than H4895 or Varget. It is still generally much better than double-base powders, so it may not be a problem at all. Because of the temperature variations where I shoot and because I was unsure about it, I haven't chosen to shoot it in matches as yet. I am happy to hear the reports above; it sounds like it's not much of a concern. In general, a 20 to 30 fps increase in velocity doesn't mean a huge amount. However, as long as the precision and ES/SD are comparable (which they have been), and temperature-sensitivity isn't an issue, I'll take the extra velocity from IMR4895 any time, especially in a .223 shooting 90s at 1000 yd. Every little bit helps.