Sorry Spclark you posted before I got done...
Whats the Berger load data say?
I would back off 1 full grain and work back up 1/2 grain at a time.
If 44 gr was the sweet spot for the 168 eldm, I would back down to 43gr and re work the load up to 45'ish grains
Full 20 % Depends on case volume
Depends on how bullets’ bearing surface length differs; longer surface = more resistance to engraving by lands when fired, higher pressures.
Too, if BTO dimension changes, and both bullets are seated to same dimension - either on or off lands - higher pressures will occur when longer bullet’s fired. Reason being, longer bullet will reduce case capacity more than shorter one.
Am still learning how to use QuickLOAD, but it has been well worth the $160 when it comes to answering questions like those asked by the OP.