Have schwacked p-dogs past 750yds with my old 6x45 , 1:10twist 70Bkings. With an accurate range & good dope, just gotta get the wind call right. Accuracy is there, its a very mild mannered & barrel friendly cartridge...
When shot next to my .20TAC, the .20TAC smoked the 6x45 in trajectory. But the necked down hotrod ran hot, sooner, while the 6x45 just kept pluggin' along like a Yoeman farmer.
In a bolt gun, the 6x45AI is a great option for volume p-dog rifle. Availability of components, easy to load for, budget friendly & long barrel life are four things I'd think were important to a p-dogger?
Those little potbellies don't mind dying while you're fireforming, and once ya do, you'll never have to trim all those cases! Might not sound like much, until it's time time trim 2000 pieces of brass!
Once 'Improved', the 6x45AI is near matching the 6PPC in case capacity (performance). IE, lots to like on such a modest powder charge...
Your choice whether to go slow, or fast twist. If you shots are <300yds, ya might enjoy a bit more "SPLAT" from a 55-70gr bullet/slow twist. But if ya wanna lob 'em out there, a 1:8 throwin' 80-95gr bullets will make you a fan & handle the breeze better...
In closing, the 6x45 is simple & phenomenal! Great in an AR, and even better in a bolt gun. The Improved version just adds another dash of awesome sauce on top...
Have fun!