Looking to get a light weight, winter walking rifle in one of these calibers. The problem I have noticed is that 223s available in a one in nine twist rate are plentiful while a fast twist rate in the 22-250 is almost always one in fourteen. The game would be from head shot grouse and Turkey to mountain lion in size. So slower bullit out of a 223 such as a 60 grain Nosler partition or lighter and faster 50 grainers in the 22-250? Will the one in fourteen twist rate in the 22-250 stabilize 60 grain pills to keep them accurate? There are a lot of heavier bullit weights in factory loaded 223 ammo also. I have seen lions killed with 222 Rem and even 221 Fireball when treed. I no longer have this option since hound hunting is banned in this state. Ranges would be up to 300 yards but mostly under 100.