Bill, this is a very good and interesting question, but quite possibly few answers. Yes, as Ezell says, after leaving muzzle....you got what you got! I'm in line with that, but this interesting question could be bordering on a question I asked on the competition forum on May 30.
Is it possible that what some refer as dead air and especially the first couple of inches upon exit, have something to do with this issue, as humidity changes?? The various humidity changes when meeting up with spent nitrocellulose gases that weigh much more.... may cause the bullet to get upset a bit easier.
Example: Air den 60F, 1 ATM dry .0763 lb/cf
moist 90% den 60F, 1 ATM .0759 lb/cf
Oxygen same conditions .084 lb/cf
CO2 same conditions .117 lb/cf.....this could very well be 86% of the spent gas along with remaining nitrogen and hydrogen. Hydrogen won't be a big contributor to the weight. see attachment
The spent gas ahead of the bullet meets up with ATM air before leaving the barrel and the density differences due to humidity might possibly be the differences in "tune" we are talking about. This the reason you may have to move the tuner as much as you do or change the load a bit.
My two cents! However, no real answer, but question is a great one!