The 4thou crush will always work,, I see it as a good starting point. 'Best' will be what the gun tells you.
I have logged 2thou for F205 and WSR, 4thou for F210, and 5thou for BR4.
But this is post tweaking results in load development per my primer striking and loads.
It's probably hard to imagine this as a matter to lose sleep about. I don't, because I measure and set em all the same.
And barring serious problems, any bottomed primers will fire.
I doubt it would matter with 6PPC pressure loads, nor for large capacity cartridges(7WSM, +).
But for 223, 6br, 6xc, 6.5wssm capacity loads, I can see primer/striking adjustments just like I can see CBTO and tension adjustments.
Speaking of striking; If you haven't, it's worth while to spend a day testing trigger hangers, firing pin protrusion and spring force for best precision. Get your bolt handle stable through pin release. Make sure the cocking piece is not giving up energy on release. This potentially being inconsistent, depending on bolt turned to position. Makes sure the spring can't bind in the bolt.
Optimization of striking can give you better than you thought from your load. You need at least one thing that is always fixed in this, and a set primer pre-loading provides this.
Ever notice how random primer choice has always been? We trial & error for whatever primer works best in this & that gun -even while they all fire. I don't think it's the primers themselves. I think it's our seating and striking of them, and that it's possible to optimize this for any one primer chosen. Just like it's possible to optimize seating for each chosen bullet.
If you adjust released pin protrusion, group shooting 20thou at a time, in mid-capacity cartridges anyway, you'll see grouping open, close, and reopen along the way.
Primer seating is slower with manual operations the indicated K&M takes you to. Bullet seating is slower where you verify each. Powder charging is slower where you measure each. Good ammo making is not a race.