I'd recommend that you pick a chambering that will push a bullet of at least a .6 BC to a minimum velocity of 2950 fps, or the next faster accuracy node of around 3100-3150 fps. BC rules 1,000 yard shooting, a high BC bullet sheds velocity more slowly, which allows for a shorter time of flight to the target, which gives the wind less time to act on the bullet.
If I were to start over again I might entertain the thought of a .30 short magnum, especially since Norma has started producing .300 RSAUM brass.
Not having a lot of spare time to work on things, I viewed my build as a system and chose accordingly. At the time, 6.5 X 284 Lapua or Norma brass allowed a .297" no turn neck chamber and 2950 fps with a high BC bullet with recoil levels suitable for a light rifle without a brake. The learning curve wasn't too bad but limited time stretched out the developement. Now I have a load, a rifle that shoots better in the wind than it should, decent dope, my own spec reamer so rebarreling is as consistant as possible, and a few wins at the local matches I can make.
Since the system is well developed, and since it is successful, it remains my primary rifle. There are one or two other projects in progress, but none as successful (yet). Which tends to prove one point, there are no magic powders or bullets or chamberings. Pick something which has a good chance of working and stick with it. Once you have enough experience, you can make up your own mind about what's next or if there should be a next.
The three Bs were mentioned. Pick a barrel. Get your bullets and brass, load a couple of dummy rounds and determine the neck diameter and COL you want to spec the reamer to. The other part of the reamer equation for me is that it is dimensioned to work with a Redding neck bushing FL sizing die. Keeps loading simple, the no turn neck keeps brass prep minimal. The concept works with any chambering.
And find a good smith. All the best compnents in the world are wasted if the rifle isn't built right in the first place.