And, in my 7X57 which has case capacity closer to the 308 than the 7.5X55, QuickLoad favors the RL-17 and that is proven by my test loads.
Precisely - you're agreeing with me. It's the ratio of case capacity / charge weight to bore diameter which is crucial in any powder choice with the third factor of bullet weight (inertia) thrown into the mix.
The 4350s are 'standard powders' for 7X57mm with its significantly smaller bore area and as a result, a very different 'effective expansion ratio' to a similar case-capacity thirty-calibre design. I happily used Viht N160, slower burning still than the 4350s and Re17 in 7X57mm when I used to load the cartridge many years back for a German manufactured South African Mauser 'long rifle', a Boer War relic. I'd never consider even trying N160 in any 308 Win combination even with the new 230gn Berger. Re17 has a similar burning speed to IMR/Accurate/H4350, and insofar as burning rate comparisons are valid, which one must always take with a certain pinch of salt, means it should perform well in the same applications as those powders.
If one takes QuickLOAD calculated MVs as the ultimate indicator of efficiency, a not unreasonable assumption, my experience is that it doesn't always work out that way in practice for some reason with Re17. I'm constantly struck by the number of combinations which the program lists the powder as providing the highest MV, but when I and others try those combinations on the range often find them disappointing. 'In this sort of theory world', 6.5-284 and Re17 should be ideal partners for instance, but not that many people have actually adopted the powder after trying it.
I was surprised and disappointed to find that I got relatively poor results from the powder with the 185gn Berger LRBT 'Juggernaut', sheer MV figures aside. That same rifle and chamber had performed superbly with the apparently similar Viht N550. Do a QuickLOAD propellant table run for 308 with this bullet at 2.900" COAL in a 56.0gn water capacity case and Re17 is apparently right on the money - 1st equal MV (2,811 fps) with W760/H414, 102% fill-ratio, 100% charge burn. It ticks every box. N550 is ~ 60 fps behind, Varget ~90 fps down and N150 is hardly on the radar nearly 200 fps awry.
What do most experienced 1,000yd sling and F/TR shooters use behind this bullet? Viht N150 and N550 in the UK; H4895 and Varget in the US. So far as QuicKLOAD predictions go, UK F/TR competitors obtain MVs from the two Viht powders that are impossible without producing massive charge compression, and which ought to at the least wreck cases in a single firing such are the pressures likely to be generated. So, great and invaluable development tool that QuickLOAD is, this is an application where the program produces misleading results unless some iof its database values are 'tweaked'.