In my experience it can be off and is dependent on alot of variables that need to be correct, such as case volume and bullet dimensions and seating dimensions. Powder stats such as burn rate and densities also sometimes dont match reality. You need to calibrate it by starting with min loads of the same book components and record your actual velocity. If all the case volume and dimensions are set right, then you play with initial shot pressure, powder burn rate, etc to get velocity to match your measured results to “true” it. I havent used it for handguns yet but have in a variety of rifle cartridges from straight wall to overbore bottlenecks. It leaves alot to be desired as an initial guestimate but better than nothingHodgdon's data for CFE-Pistol and Titegroup loads is listing pressures much higher (like 10,000 psi) than Gordon's Reloading Tool shows. Is GRT known to be very accurate for pressure and velocity?
Remember the manual data is based on real data based on the components used. I don't like computer guestimates , especially since they give incorrect loading data that has to be corrected by fudging numbers to get it to match chrono numbers. Try to lookup data in several manuals and compare. Some companies put loading data free on line. Never try to push the limit. A medium accurate load is the safest.Hodgdon's data for CFE-Pistol and Titegroup loads is listing pressures much higher (like 10,000 psi) than Gordon's Reloading Tool shows. Is GRT known to be very accurate for pressure and velocity?