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effect of shooting two different powders back-to-back

I was shooting a Cortina ladder test with H4895 and 185 juggs. When done, I switched to a know load with varget. I saw a jump of 70-80 FPS off of what I had recorded for that load for the first 6-7 rounds, then it settled back down to where it was originally.

Rifle is a .308W with Bartlein 1:10 26"

What have you guys observed in similar situations?
 
I never shoot different powders or different bullets back to back without a complete cleaning first. The fouling is different and I have seen FPS, POI shifts and in general problems. Once it's seasoned with a load I don't change it or dabble with other stuff for the most part.
 
When I used Varget (I no longer buy it after their great 'can not get anywhere' fiasco of a few years ago) I found it to be one of the dirtiest powders I ever used. Because of that alone I did not shoot anything else until I cleaned the barrel in which it was fired.. As it disappeared I found other powders that performed as well and did not leave a sewer pipe looking barrel. At that time it seemed to me all I read was that Varget was THE only powder to be accurate in many different cartridges.
Found that not to be so.
 
In my testing, shooting different bullets, different coatings, or powders seem to produce results like what you experienced. Primers sometimes produce the effect and sometimes don't.
 
If I am going to change powders in a test, I always shoot one round with the new powder before shooting a group. It does make a difference. If you clean it, you have to shoot a fouler first anyway.
 
When I do load development testing, I mix the test groups with a known pet load as a "control" so I have mixed groups with different bullets and powders during one testing session. I have never seen any effect from mixing bullets and powder. I have read a lot of reports that say it does but my data does not show it with the type of testing I am doing. A typical testing session for me would include two or three groups of the "control" load mixed with three or four groups of the test load. I normally shoot ten shot groups and am doing testing for the AR for XTC.
 
For precision bolt action rifles, you need to expect that changes will cause change.
I do not disagree, I am just giving my experience with AR match rifles. I have also done some testing with "precision bolt action rifles" and use the same procedure of mixing a "control" with the test load and have not experienced any evidence that this causes change in the data. The level of accuracy I am working with is approximately X ring size groups or slightly smaller on the NRA XTC, mid range and long range targets (not F Class). If I were dealing with a higher level of accuracy it is probable that I would have to consider other factors to achieve a higher level. Again, I am not disagreeing with anyone, just giving my experience with mixing bullets and powder for my application.
 

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