Obviously every barrel is different to a degree. The barrel on my Dasher is a Lilja 1:8 twist, it shoots 108 Berger's fantastically out to 1K, kinda of my go to bullet that just works, jump that one 20 off. I've shot them competitively in both F Class and Sling with the same rifle.
The reason that I'm excited about the Nosler RDF's is two fold, higher BC, less wind and price, buying blems and over runs made the price per bullet really cheap. If I can get them to shoot and they buy me more wind, I win. (Figure of speech

) IMO they are a hybrid clone, so in keeping with what they say about the Berger Hybrid's, that they like jumping, it seemed like a good place to start.
My testing never showed an absolute failure at a certain setting, they all shot pretty well, but when I hit 40 off, (in my barrel) the group shrunk. One test does not make a decision. The first was at 600 yards, 40 off held the X ring on a MR-1 with irons. My last test was benched at 200 yards, 40 off shot less then 1/2 MOA (3/8?). Now I'll be looking for consistency, I'll be shooting prone irons over the next few weeks, looking for repeatable results. If so, then off to the matches with it. If it fails, I'll be buying Berger 108's.
I think that some generalities can be drawn to certain bullet types. IMO Sierra SMK's shot best being jumped a moderate amount, in some barrels 10 off, others 25 off.
I.E. The 107 SMK's shot very well from the Dasher, but, their LTO was all over the place, making a consistent loaded round more work, each had to be measured and adjusted, a real PITA. The only Sierra's I shoot now are 69 SMK's in my 223 AI, load'em and shoot'em, 20 off, or what the come out to be, they work regardless! For competition, it's Berger's or maybe the RDF's in the future.
The conventional wisdom surrounded VLD's was that they needed to be jammed or just touching, now people are jumping them significantly, 60 -80 off, and getting great results. The new Hybrids are supposed to tune easily, we'll see how it goes. Reports seem to say they RDF's shoot, whether it's touching, 10, 20 , 30 or more off, only testing can tell. Shooter's wishing to try the RDF's or any bullet, this type of information gives you a sense of what the bullet MAY like. As they say YMMV.