urbanrifleman
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I am sure that there are lots of people who did the math, but I just wanted to point out something that maybe others have never considered.
Here is 22-250 shooting a 60 grain Hornady at 3650.

Here is comparison of the same bullet with the Hornady ELDM 75 at 3350.

By 150 yards the bullets are going the same speed.
By 400 yards the velocity advantage at the muzzle has flipped.

I think it is quite possible people are burning up barrels trying to get these little varmint bullets going really fast to get more 'splody, when in fact they could shoot a milder load with a slicker bullet and get more 'splody.
Here is more extreme example. Here is the same 60 grain going 3950. And the same MILD load of 3350 of the 75.

Here you can see that the small bullet is much better for velocity at short range. That could lead to some serious splody.
But then they are going the same speed at 350 yards... and that 75 grain bullet is going to hit like a hammer.
Here is 22-250 shooting a 60 grain Hornady at 3650.

Here is comparison of the same bullet with the Hornady ELDM 75 at 3350.

By 150 yards the bullets are going the same speed.
By 400 yards the velocity advantage at the muzzle has flipped.

I think it is quite possible people are burning up barrels trying to get these little varmint bullets going really fast to get more 'splody, when in fact they could shoot a milder load with a slicker bullet and get more 'splody.
Here is more extreme example. Here is the same 60 grain going 3950. And the same MILD load of 3350 of the 75.

Here you can see that the small bullet is much better for velocity at short range. That could lead to some serious splody.
But then they are going the same speed at 350 yards... and that 75 grain bullet is going to hit like a hammer.