Just a thought... unless you are looking to shoot way beyond 400 yards shooting the 75+ grain bullets out of the 22 250 offers virtually no advantage. I built an 8 twist '250 around the 75gr amax . It knifes through the wind like a demon but I found 90% of my predator shooting is under 250 yards and I missed having a faster bullet at these ranges. I switched to 60 gr bt's. Will see this year how they work. Ymmv... good luck!