Perhaps the OP,
@outlaw1873, confused caliber with cartridge when posting the title.
I'm appreciative of other's posting their preferred cartridge. .270 is generally how 270 Winchester is referenced.
If I told you I preferred .264, .284, .308, .338 or .359 caliber, that would give you a broad range of cartridges to choose from. I think it really comes down to what gun do you prefer.
I first started with 7 Mag for over five years. Switched to 7mm/08 for another five, used a 6.5 Swede one year, my 338 Model 70 two years, and this year I haven't decided whether to use my 35 Remington, 6.5 Swede, 300 Savage, or 7mm/08. I think I'm done with the magnums.
Edit to add, heck, I might even use my 450 Bushmaster this year, since where I'll be hunting, a shot more than two hundred yards is extremely unlikely.