No doubt. Unlike a pre-bored hole, nothing to guide the cutter; it's just wobbling around in the hole if using a floating holder. Been meaning to ask Manson if they could grind a form cutter for a recessed target crown, it'd be a big time saver...
I've also ascribed to the theory that that a properly fitted pilot prevents chatter, but I haven't had the balls yet to chamber without one and risk a $3-$400 blank. I see GM has some back in stock so one of them would be a cheaper learning experience.
I'm assuming those that ascribe to the "no pilot" school (pun intended, enrolled in ground school

),
buy solid pilot reamers? It's rare that I've run into a groove dia more than a half thou under- so why spend the $$ for a live pilot?